Loading...

Optimizing DC Vaccination by Combination With Oncolytic Adenovirus Coexpressing IL-12 and GM-CSF

Dendritic cell (DC)-based vaccination is a promising strategy for cancer immunotherapy. However, clinical trials have indicated that immunosuppressive microenvironments induced by tumors profoundly suppress antitumor immunity and inhibit vaccine efficacy, resulting in insufficient reduction of tumor...

Full description

Saved in:
Bibliographic Details
Main Authors: Zhang, Song-Nan, Choi, Il-Kyu, Huang, Jing-Hua, Yoo, Ji-Young, Choi, Kyung-Ju, Yun, Chae-Ok
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2011
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3149171/
https://ncbi.nlm.nih.gov/pubmed/21468000
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2011.29
Tags: Add Tag
No Tags, Be the first to tag this record!