Optimizing DC Vaccination by Combination With Oncolytic Adenovirus Coexpressing IL-12 and GM-CSF

Dendritic cell (DC)-based vaccination is a promising strategy for cancer immunotherapy. However, clinical trials have indicated that immunosuppressive microenvironments induced by tumors profoundly suppress antitumor immunity and inhibit vaccine efficacy, resulting in insufficient reduction of tumor...

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Bibliographic Details
Main Authors: Zhang, Song-Nan, Choi, Il-Kyu, Huang, Jing-Hua, Yoo, Ji-Young, Choi, Kyung-Ju, Yun, Chae-Ok
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2011
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Original Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3149171/
https://ncbi.nlm.nih.gov/pubmed/21468000
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2011.29
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