Optimizing DC Vaccination by Combination With Oncolytic Adenovirus Coexpressing IL-12 and GM-CSF

Dendritic cell (DC)-based vaccination is a promising strategy for cancer immunotherapy. However, clinical trials have indicated that immunosuppressive microenvironments induced by tumors profoundly suppress antitumor immunity and inhibit vaccine efficacy, resulting in insufficient reduction of tumor...

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Detalles Bibliográficos
Autores principales: Zhang, Song-Nan, Choi, Il-Kyu, Huang, Jing-Hua, Yoo, Ji-Young, Choi, Kyung-Ju, Yun, Chae-Ok
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group 2011
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Original Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3149171/
https://ncbi.nlm.nih.gov/pubmed/21468000
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2011.29
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