Use of an Oncolytic Virus Secreting GM-CSF as Combined Oncolytic and Immunotherapy for Treatment of Colorectal and Hepatic Adenocarcinomas

Oncolytic cancer therapy using herpes simplex viruses (HSV) that have direct tumoricidal effects and cancer immunotherapy using the cytokine granulocyte-macrophage colony-stimulating factor (GM-CSF) have each been effective in preclinical testing. NV1034 is a multi-mutated oncolytic HSV carrying the...

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Hlavní autoři: Malhotra, Sandeep, Kim, Teresa, Zager, Jonathan, Bennett, Joseph, Ebright, Michael, D’Angelica, Michael, Fong, Yuman
Médium: Artigo
Jazyk:Inglês
Vydáno: 2007
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2559995/
https://ncbi.nlm.nih.gov/pubmed/17383529
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.surg.2006.10.010
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