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Functional Genomic mRNA Profiling of Colorectal Adenomas: Identification and in vivo Validation of CD44 and Splice Variant CD44v6 as Molecular Imaging Targets

Colorectal cancer (CRC) is the third leading cause of cancer-related deaths worldwide. High adenoma miss rates, especially seen in high-risk patients, demand for better endoscopic detection. By fluorescently 'highlighting' specific molecular characteristics, endoscopic molecular imaging ha...

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Bibliographische Detailangaben
Veröffentlicht in:Theranostics
Hauptverfasser: Hartmans, Elmire, Orian-Rousseau, Veronique, Matzke-Ogi, Alexandra, Karrenbeld, Arend, de Groot, Derk Jan A., de Jong, Steven, van Dam, Gooitzen M., Fehrmann, Rudolf S.N., Nagengast, Wouter B.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Ivyspring International Publisher 2017
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5327362/
https://ncbi.nlm.nih.gov/pubmed/28255344
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/thno.16816
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