Toll‐like receptor 4 signalling mediates inflammation in skeletal muscle of patients with chronic kidney disease

BACKGROUND: Inflammation in skeletal muscle is implicated in the pathogenesis of insulin resistance and cachexia but why uremia up‐regulates pro‐inflammatory cytokines is unknown. Toll‐like receptors (TLRs) regulate locally the innate immune responses, but it is unknown whether in chronic kidney dis...

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Detalhes bibliográficos
Publicado no:J Cachexia Sarcopenia Muscle
Main Authors: Verzola, Daniela, Bonanni, Alice, Sofia, Antonella, Montecucco, Fabrizio, D'Amato, Elena, Cademartori, Valeria, Parodi, Emanuele Luigi, Viazzi, Francesca, Venturelli, Chiara, Brunori, Giuliano, Garibotto, Giacomo
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2016
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Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5326826/
https://ncbi.nlm.nih.gov/pubmed/27897392
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcsm.12129
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