Insulin sensitivity of muscle protein metabolism is altered in patients with chronic kidney disease and metabolic acidosis

An emergent hypothesis is that a resistance to the anabolic drive by insulin may contribute to loss of strength and muscle mass in patients with chronic kidney disease (CKD). We tested whether insulin resistance extends to protein metabolism using the forearm perfusion method with arterial insulin i...

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Detalhes bibliográficos
Publicado no:Kidney Int
Principais autores: Garibotto, Giacomo, Sofia, Antonella, Russo, Rodolfo, Paoletti, Ernesto, Bonanni, Alice, Parodi, Emanuele L, Viazzi, Francesca, Verzola, Daniela
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
Assuntos:
Clinical Investigation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4678169/
https://ncbi.nlm.nih.gov/pubmed/26308671
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ki.2015.247
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