Principles Governing A-to-I RNA Editing in the Breast Cancer Transcriptome

Little is known about how RNA editing operates in cancer. Transcriptome analysis of 68 normal and cancerous breast tissues revealed that the editing enzyme ADAR acts uniformly, on the same loci, across tissues. In controlled ADAR expression experiments, the editing frequency increased at all loci wi...

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Detalhes bibliográficos
Publicado no:Cell Rep
Main Authors: Fumagalli, Debora, Gacquer, David, Rothé, Françoise, Lefort, Anne, Libert, Frederick, Brown, David, Kheddoumi, Naima, Shlien, Adam, Konopka, Tomasz, Salgado, Roberto, Larsimont, Denis, Polyak, Kornelia, Willard-Gallo, Karen, Desmedt, Christine, Piccart, Martine, Abramowicz, Marc, Campbell, Peter J., Sotiriou, Christos, Detours, Vincent
Formato: Artigo
Idioma:Inglês
Publicado em: Cell Press 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5326813/
https://ncbi.nlm.nih.gov/pubmed/26440892
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2015.09.032
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