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Association between SPARC mRNA Expression, Prognosis and Response to Neoadjuvant Chemotherapy in Early Breast Cancer: A Pooled in-silico Analysis

INTRODUCTION: SPARC is an important regulator of the extracellular matrix and has been suggested to improve delivery of albumin-bound cytotoxics. However, little is known regarding its role in breast cancer (BC). METHODS: We conducted a pooled analysis of publically available datasets, in which BC p...

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Main Authors: Azim, Hatem A., Singhal, Sandeep, Ignatiadis, Michail, Desmedt, Christine, Fumagalli, Debora, Veys, Isabelle, Larsimont, Denis, Piccart, Martine, Michiels, Stefan, Sotiriou, Christos
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2013
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Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3637211/
https://ncbi.nlm.nih.gov/pubmed/23638089
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0062451
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