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Principles Governing A-to-I RNA Editing in the Breast Cancer Transcriptome

Little is known about how RNA editing operates in cancer. Transcriptome analysis of 68 normal and cancerous breast tissues revealed that the editing enzyme ADAR acts uniformly, on the same loci, across tissues. In controlled ADAR expression experiments, the editing frequency increased at all loci wi...

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Podrobná bibliografie
Vydáno v:Cell Rep
Hlavní autoři: Fumagalli, Debora, Gacquer, David, Rothé, Françoise, Lefort, Anne, Libert, Frederick, Brown, David, Kheddoumi, Naima, Shlien, Adam, Konopka, Tomasz, Salgado, Roberto, Larsimont, Denis, Polyak, Kornelia, Willard-Gallo, Karen, Desmedt, Christine, Piccart, Martine, Abramowicz, Marc, Campbell, Peter J., Sotiriou, Christos, Detours, Vincent
Médium: Artigo
Jazyk:Inglês
Vydáno: Cell Press 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5326813/
https://ncbi.nlm.nih.gov/pubmed/26440892
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2015.09.032
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