Mitochondrial DNA Activates the NLRP3 Inflammasome and Predisposes to Type 1 Diabetes in Murine Model

Although a correlation between polymorphisms of NOD-like receptor family-pyrin domain containing 3 (NLRP3) and predisposition to type 1 diabetes (T1D) has been identified, the potential function and activation of the NLRP3 inflammasome in T1D have not been clarified. The present study shows that non...

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Detalles Bibliográficos
Publicado en:Front Immunol
Main Authors: Carlos, Daniela, Costa, Frederico R. C., Pereira, Camila A., Rocha, Fernanda A., Yaochite, Juliana N. U., Oliveira, Gabriela G., Carneiro, Fernando S., Tostes, Rita C., Ramos, Simone G., Zamboni, Dario S., Camara, Niels O. S., Ryffel, Bernhard, Silva, João S.
Formato: Artigo
Idioma:Inglês
Publicado: Frontiers Media S.A. 2017
Assuntos:
Immunology
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5326761/
https://ncbi.nlm.nih.gov/pubmed/28289409
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2017.00164
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