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A Blueprint for a Synthetic Genetic Feedback Controller to Reprogram Cell Fate
To artificially reprogram cell fate, experimentalists manipulate the gene regulatory networks (GRNs) that maintain a cell’s phenotype. In practice, reprogramming is often performed by constant overexpression of specific transcription factors (TFs). This process can be unreliable and inefficient. Her...
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| Publicado en: | Cell Syst |
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| Autores principales: | , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2017
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5326680/ https://ncbi.nlm.nih.gov/pubmed/28065574 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cels.2016.12.001 |
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