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S6K1 Phosphorylation of H2B Mediates EZH2 Trimethylation of H3: A Determinant of Early Adipogenesis

S6K1 has been implicated in a number of key metabolic responses, which contribute to obesity. Critical among these is the control of a transcriptional program required for the commitment of mesenchymal stem cells to the adipocytic lineage. However, in contrast to its role in the cytosol, the functio...

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Detalhes bibliográficos
Publicado no:Mol Cell
Main Authors: Yi, Sang Ah, Um, Sung Hee, Lee, Jaecheol, Yoo, Ji Hee, Bang, So Young, Park, Eun Kyung, Lee, Min Gyu, Nam, Ki Hong, Jeon, Ye Ji, Park, Jong Woo, You, Jueng Soo, Lee, Sang-Jin, Bae, Gyu-Un, Rhie, Jong Won, Kozma, Sara C., Thomas, George, Han, Jeung-Whan
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5325705/
https://ncbi.nlm.nih.gov/pubmed/27151441
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2016.03.011
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