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Histone H3K27 methyltransferase Ezh2 represses Wnt genes to facilitate adipogenesis
Wnt/β-catenin signaling inhibits adipogenesis. Genome-wide profiling studies have revealed the enrichment of histone H3K27 methyltransferase Ezh2 on Wnt genes. However, the functional significance of such a direct link between the two types of developmental regulators in mammalian cells, and the rol...
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| Hauptverfasser: | , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
National Academy of Sciences
2010
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2867706/ https://ncbi.nlm.nih.gov/pubmed/20368440 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1000031107 |
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