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Histone H3K27 methyltransferase Ezh2 represses Wnt genes to facilitate adipogenesis

Wnt/β-catenin signaling inhibits adipogenesis. Genome-wide profiling studies have revealed the enrichment of histone H3K27 methyltransferase Ezh2 on Wnt genes. However, the functional significance of such a direct link between the two types of developmental regulators in mammalian cells, and the rol...

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Detalhes bibliográficos
Main Authors: Wang, Lifeng, Jin, Qihuang, Lee, Ji-Eun, Su, I-hsin, Ge, Kai
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2867706/
https://ncbi.nlm.nih.gov/pubmed/20368440
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1000031107
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