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Histone H3K9 methyltransferase G9a represses PPARγ expression and adipogenesis

PPARγ promotes adipogenesis while Wnt proteins inhibit adipogenesis. However, the mechanisms that control expression of these positive and negative master regulators of adipogenesis remain incompletely understood. By genome-wide histone methylation profiling in preadipocytes, we find that among gene...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Wang, Lifeng, Xu, Shiliyang, Lee, Ji-Eun, Baldridge, Anne, Grullon, Sean, Peng, Weiqun, Ge, Kai
Format: Artigo
Sprache:Inglês
Veröffentlicht: European Molecular Biology Organization 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3545301/
https://ncbi.nlm.nih.gov/pubmed/23178591
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2012.306
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