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Histone H3K9 methyltransferase G9a represses PPARγ expression and adipogenesis

PPARγ promotes adipogenesis while Wnt proteins inhibit adipogenesis. However, the mechanisms that control expression of these positive and negative master regulators of adipogenesis remain incompletely understood. By genome-wide histone methylation profiling in preadipocytes, we find that among gene...

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Bibliografische gegevens
Hoofdauteurs: Wang, Lifeng, Xu, Shiliyang, Lee, Ji-Eun, Baldridge, Anne, Grullon, Sean, Peng, Weiqun, Ge, Kai
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: European Molecular Biology Organization 2013
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3545301/
https://ncbi.nlm.nih.gov/pubmed/23178591
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2012.306
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