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Histone H3K9 methyltransferase G9a represses PPARγ expression and adipogenesis

PPARγ promotes adipogenesis while Wnt proteins inhibit adipogenesis. However, the mechanisms that control expression of these positive and negative master regulators of adipogenesis remain incompletely understood. By genome-wide histone methylation profiling in preadipocytes, we find that among gene...

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Detalles Bibliográficos
Main Authors: Wang, Lifeng, Xu, Shiliyang, Lee, Ji-Eun, Baldridge, Anne, Grullon, Sean, Peng, Weiqun, Ge, Kai
Formato: Artigo
Idioma:Inglês
Publicado: European Molecular Biology Organization 2013
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3545301/
https://ncbi.nlm.nih.gov/pubmed/23178591
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2012.306
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