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Histone H3K9 methyltransferase G9a represses PPARγ expression and adipogenesis

PPARγ promotes adipogenesis while Wnt proteins inhibit adipogenesis. However, the mechanisms that control expression of these positive and negative master regulators of adipogenesis remain incompletely understood. By genome-wide histone methylation profiling in preadipocytes, we find that among gene...

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Autori principali: Wang, Lifeng, Xu, Shiliyang, Lee, Ji-Eun, Baldridge, Anne, Grullon, Sean, Peng, Weiqun, Ge, Kai
Natura: Artigo
Lingua:Inglês
Pubblicazione: European Molecular Biology Organization 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3545301/
https://ncbi.nlm.nih.gov/pubmed/23178591
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2012.306
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