S6K1 Phosphorylation of H2B Mediates EZH2 Trimethylation of H3: A Determinant of Early Adipogenesis

S6K1 has been implicated in a number of key metabolic responses, which contribute to obesity. Critical among these is the control of a transcriptional program required for the commitment of mesenchymal stem cells to the adipocytic lineage. However, in contrast to its role in the cytosol, the functio...

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Publicat a:Mol Cell
Autors principals: Yi, Sang Ah, Um, Sung Hee, Lee, Jaecheol, Yoo, Ji Hee, Bang, So Young, Park, Eun Kyung, Lee, Min Gyu, Nam, Ki Hong, Jeon, Ye Ji, Park, Jong Woo, You, Jueng Soo, Lee, Sang-Jin, Bae, Gyu-Un, Rhie, Jong Won, Kozma, Sara C., Thomas, George, Han, Jeung-Whan
Format: Artigo
Idioma:Inglês
Publicat: 2016
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5325705/
https://ncbi.nlm.nih.gov/pubmed/27151441
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2016.03.011
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