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RSL3 and Erastin differentially regulate redox signaling to promote Smac mimetic-induced cell death

Redox mechanisms play an important role in the control of various signaling pathways. Here, we report that Second mitochondrial activator of caspases (Smac) mimetic-induced cell death is regulated by redox signaling. We show that RSL3, a glutathione (GSH) peroxidase (GPX) 4 inhibitor, or Erastin, an...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Dächert, Jasmin, Schoeneberger, Hannah, Rohde, Katharina, Fulda, Simone
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5325403/
https://ncbi.nlm.nih.gov/pubmed/27588473
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.11687
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