Hypoxia inducible factor-1 mediates the expression of the immune checkpoint HLA-G in glioma cells through hypoxia response element located in exon 2

HLA-G is an immune checkpoint molecule with specific relevance in cancer immunotherapy. It was first identified in cytotrophoblasts, protecting the fetus from maternal rejection. HLA-G tissue expression is very restricted but induced in numerous malignant tumors such as glioblastoma, contributing to...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:Oncotarget
Hlavní autoři: Yaghi, Layale, Poras, Isabelle, Simoes, Renata T., Donadi, Eduardo A., Tost, Jörg, Daunay, Antoine, de Almeida, Bibiana Sgorla, Carosella, Edgardo D., Moreau, Philippe
Médium: Artigo
Jazyk:Inglês
Vydáno: Impact Journals LLC 2016
Témata:
Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5325396/
https://ncbi.nlm.nih.gov/pubmed/27577073
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.11628
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky