NAD(+): The convergence of DNA repair and mitophagy

ATM is a 350 kDa serine/threonine kinase best known for its role in DNA repair and multiple cellular homeostasis pathways. Mutation in ATM causes the disease ataxia telangiectasia (A-T) with clinical features including ataxia, severe cerebellar atrophy and Purkinje cell loss. In a cross-species stud...

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Bibliographic Details
Published in:Autophagy
Main Authors: Fang, Evandro F., Bohr, Vilhelm A.
Format: Artigo
Language:Inglês
Published: Taylor & Francis 2016
Subjects:
Autophagic Puncta
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5324847/
https://ncbi.nlm.nih.gov/pubmed/27929719
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15548627.2016.1257467
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