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Central role of PI3K–SYK interaction in fibrinogen‐induced lamellipodia and filopodia formation in platelets

The WAVE complex‐1, a complex of WAVE, Abi1, NAP1, PIR121, HSPC300, RacGTP and Arp2/3 proteins, and WASP complex‐1, a complex of WASP, Cdc42, PIP2, and Arp2/3 proteins, are involved in lamellipodia and filopodia formation, respectively. It is known that the two complexes have opposite dynamics. Furt...

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Bibliografiske detaljer
Udgivet i:FEBS Open Bio
Hovedforfatter: Singh, Raghvendra
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5324771/
https://ncbi.nlm.nih.gov/pubmed/28255536
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/2211-5463.12149
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