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Effects of Aicardi-Goutières syndrome mutations predicted from ADAR-RNA structures

Adenosine (A) to inosine (I) RNA editing is important for life in metazoan organisms. Dysregulation or mutations that compromise the efficacy of A to I editing results in neurological disorders and a shorten life span. These reactions are catalyzed by adenosine deaminases acting on RNA (ADARs), whic...

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Detalhes bibliográficos
Publicado no:RNA Biol
Main Authors: Fisher, Andrew J., Beal, Peter A.
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5324757/
https://ncbi.nlm.nih.gov/pubmed/27937139
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15476286.2016.1267097
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