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Effects of Aicardi-Goutières syndrome mutations predicted from ADAR-RNA structures
Adenosine (A) to inosine (I) RNA editing is important for life in metazoan organisms. Dysregulation or mutations that compromise the efficacy of A to I editing results in neurological disorders and a shorten life span. These reactions are catalyzed by adenosine deaminases acting on RNA (ADARs), whic...
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出版年: | RNA Biol |
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主要な著者: | , |
フォーマット: | Artigo |
言語: | Inglês |
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Taylor & Francis
2016
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主題: | |
オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5324757/ https://ncbi.nlm.nih.gov/pubmed/27937139 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15476286.2016.1267097 |
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