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In vitro activation of coagulation by human neutrophil DNA and histone proteins but not neutrophil extracellular traps

NETosis is a physiologic process in which neutrophils release their nuclear material in the form of neutrophil extracellular traps (NETs). NETs have been reported to directly promote thrombosis in animal models. Although the effects of purified NET components including DNA, histone proteins, and neu...

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Publicado en:Blood
Main Authors: Noubouossie, Denis F., Whelihan, Matthew F., Yu, Yuan-Bin, Sparkenbaugh, Erica, Pawlinski, Rafal, Monroe, Dougald M., Key, Nigel S.
Formato: Artigo
Idioma:Inglês
Publicado: American Society of Hematology 2017
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5324715/
https://ncbi.nlm.nih.gov/pubmed/27919911
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2016-06-722298
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