Dietary intervention, but not losartan, completely reverses non-alcoholic steatohepatitis in obese and insulin resistant mice

BACKGROUND: Dietary intervention is the cornerstone of non-alcoholic steatohepatitis (NASH) treatment. However, histological evidence of its efficacy is limited and its impact on hepatic pathways involved in NASH is underreported. The efficacy of the angiotensin receptor type 1 blocker losartan is c...

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Enregistré dans:
Détails bibliographiques
Publié dans:Lipids Health Dis
Auteurs principaux: Verbeek, Jef, Spincemaille, Pieter, Vanhorebeek, Ilse, Van den Berghe, Greet, Vander Elst, Ingrid, Windmolders, Petra, van Pelt, Jos, van der Merwe, Schalk, Bedossa, Pierre, Nevens, Frederik, Cammue, Bruno, Thevissen, Karin, Cassiman, David
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2017
Sujets:
Research
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5324232/
https://ncbi.nlm.nih.gov/pubmed/28231800
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12944-017-0432-7
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