Dietary intervention, but not losartan, completely reverses non-alcoholic steatohepatitis in obese and insulin resistant mice

BACKGROUND: Dietary intervention is the cornerstone of non-alcoholic steatohepatitis (NASH) treatment. However, histological evidence of its efficacy is limited and its impact on hepatic pathways involved in NASH is underreported. The efficacy of the angiotensin receptor type 1 blocker losartan is c...

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Publicado en:Lipids Health Dis
Autores principales: Verbeek, Jef, Spincemaille, Pieter, Vanhorebeek, Ilse, Van den Berghe, Greet, Vander Elst, Ingrid, Windmolders, Petra, van Pelt, Jos, van der Merwe, Schalk, Bedossa, Pierre, Nevens, Frederik, Cammue, Bruno, Thevissen, Karin, Cassiman, David
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2017
Materias:
Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5324232/
https://ncbi.nlm.nih.gov/pubmed/28231800
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12944-017-0432-7
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