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The chaperone-like activity of the hepatitis C virus IRES and CRE elements regulates genome dimerization

The RNA genome of the hepatitis C virus (HCV) establishes a network of long-distance RNA-RNA interactions that direct the progression of the infective cycle. This work shows that the dimerization of the viral genome, which is initiated at the dimer linkage sequence (DLS) within the 3′UTR, is promote...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Romero-López, Cristina, Barroso-delJesus, Alicia, Berzal-Herranz, Alfredo
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5324077/
https://ncbi.nlm.nih.gov/pubmed/28233845
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep43415
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