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Selection of targets and the most efficient hairpin ribozymes for inactivation of mRNAs using a self-cleaving RNA library

The identification of proficient target sites within long RNA molecules, as well as the most efficient ribozymes for each, is a major concern for the use of ribozymes as gene suppressers. In vitro selection methods using combinatorial libraries are powerful tools for the rapid elucidation of interac...

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Bibliografske podrobnosti
Main Authors: Barroso-delJesus, Alicia, Berzal-Herranz, Alfredo
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2001
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1084165/
https://ncbi.nlm.nih.gov/pubmed/11743025
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/embo-reports/kve247
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