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Selection of targets and the most efficient hairpin ribozymes for inactivation of mRNAs using a self-cleaving RNA library
The identification of proficient target sites within long RNA molecules, as well as the most efficient ribozymes for each, is a major concern for the use of ribozymes as gene suppressers. In vitro selection methods using combinatorial libraries are powerful tools for the rapid elucidation of interac...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2001
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1084165/ https://ncbi.nlm.nih.gov/pubmed/11743025 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/embo-reports/kve247 |
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