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The folding of the hepatitis C virus internal ribosome entry site depends on the 3′-end of the viral genome

Hepatitis C virus (HCV) translation initiation is directed by an internal ribosome entry site (IRES) and regulated by distant regions at the 3′-end of the viral genome. Through a combination of improved RNA chemical probing methods, SHAPE structural analysis and screening of RNA accessibility using...

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Autors principals: Romero-López, Cristina, Barroso-delJesus, Alicia, García-Sacristán, Ana, Briones, Carlos, Berzal-Herranz, Alfredo
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2012
Matèries:
RNA
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3526292/
https://ncbi.nlm.nih.gov/pubmed/23066110
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gks927
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