A magnesium-induced RNA conformational switch at the internal ribosome entry site of hepatitis C virus genome visualized by atomic force microscopy

The 5′ untranslated region of hepatitis C virus (HCV) genomic RNA contains an internal ribosome entry site (IRES) element, composed of domains II–IV, which is required for cap-independent translation initiation. Little information on the 3D structure of the whole functional HCV IRES is still availab...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: García-Sacristán, Ana, Moreno, Miguel, Ariza-Mateos, Ascensión, López-Camacho, Elena, Jáudenes, Rosa M., Vázquez, Luis, Gómez, Jordi, Martín-Gago, José Ángel, Briones, Carlos
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2015
Assuntos:
RNA
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4288189/
https://ncbi.nlm.nih.gov/pubmed/25510496
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gku1299
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