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In vitro characterization of a miR-122-sensitive double-helical switch element in the 5′ region of hepatitis C virus RNA

It has been proposed that the hepatitis C virus (HCV) internal ribosome entry site (IRES) resides within a locked conformation, owing to annealing of its immediate flanking sequences. In this study, structure probing using Escherichia coli dsRNA-specific RNase III and other classical tools showed th...

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Main Authors: Díaz-Toledano, Rosa, Ariza-Mateos, Ascensión, Birk, Alex, Martínez-García, Belén, Gómez, Jordi
格式: Artigo
語言:Inglês
出版: Oxford University Press 2009
主題:
RNA
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2760801/
https://ncbi.nlm.nih.gov/pubmed/19578061
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkp553
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