Attenuated secretion of glucose-dependent insulinotropic polypeptide (GIP) does not alleviate hyperphagic obesity and insulin resistance in ob/ob mice

OBJECTIVE: Glucose-dependent insulinotropic polypeptide (GIP) is released during meals and promotes nutrient uptake and storage. GIP receptor knockout mice are protected from diet induced weight gain and thus GIP antagonists have been proposed as a treatment for obesity. In this study, we assessed t...

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Dades bibliogràfiques
Publicat a:Mol Metab
Autors principals: Shimazu-Kuwahara, Satoko, Harada, Norio, Yamane, Shunsuke, Joo, Erina, Sankoda, Akiko, Kieffer, Timothy J., Inagaki, Nobuya
Format: Artigo
Idioma:Inglês
Publicat: Elsevier 2017
Matèries:
Brief Communication
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5324019/
https://ncbi.nlm.nih.gov/pubmed/28271035
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmet.2017.01.006
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