Attenuated secretion of glucose-dependent insulinotropic polypeptide (GIP) does not alleviate hyperphagic obesity and insulin resistance in ob/ob mice

OBJECTIVE: Glucose-dependent insulinotropic polypeptide (GIP) is released during meals and promotes nutrient uptake and storage. GIP receptor knockout mice are protected from diet induced weight gain and thus GIP antagonists have been proposed as a treatment for obesity. In this study, we assessed t...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Mol Metab
Päätekijät: Shimazu-Kuwahara, Satoko, Harada, Norio, Yamane, Shunsuke, Joo, Erina, Sankoda, Akiko, Kieffer, Timothy J., Inagaki, Nobuya
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Elsevier 2017
Aiheet:
Brief Communication
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5324019/
https://ncbi.nlm.nih.gov/pubmed/28271035
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmet.2017.01.006
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