Bezafibrate ameliorates diabetes via reduced steatosis and improved hepatic insulin sensitivity in diabetic TallyHo mice

OBJECTIVE: Recently, we have shown that Bezafibrate (BEZ), the pan-PPAR (peroxisome proliferator-activated receptor) activator, ameliorated diabetes in insulin deficient streptozotocin treated diabetic mice. In order to study whether BEZ can also improve glucose metabolism in a mouse model for fatty...

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Detalhes bibliográficos
Publicado no:Mol Metab
Main Authors: Franko, Andras, Neschen, Susanne, Rozman, Jan, Rathkolb, Birgit, Aichler, Michaela, Feuchtinger, Annette, Brachthäuser, Laura, Neff, Frauke, Kovarova, Marketa, Wolf, Eckhard, Fuchs, Helmut, Häring, Hans-Ulrich, Peter, Andreas, Hrabě de Angelis, Martin
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2017
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5323884/
https://ncbi.nlm.nih.gov/pubmed/28271032
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmet.2016.12.007
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