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TallyHO obese female mice experience poor reproductive outcomes and abnormal blastocyst metabolism which is reversed by metformin

OBJECTIVE: Obese women experience worse reproductive outcomes compared to normal weight women, specifically infertility, pregnancy loss, fetal malformations and developmental delay. The objective of this study was to use a genetic mouse model of obesity in order to recapitulate the human reproductiv...

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Enregistré dans:
Détails bibliographiques
Publié dans:Reprod Fertil Dev
Auteurs principaux: Louden, Erica D., Luzzo, Kerri M., Jimenez, Patricia T., Chi, Tiffany, Chi, Maggie, Moley, Kelle H.
Format: Artigo
Langue:Inglês
Publié: 2014
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4365903/
https://ncbi.nlm.nih.gov/pubmed/25472042
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1071/RD14339
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