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Adipocyte-specific deficiency of NADPH oxidase 4 delays the onset of insulin resistance and attenuates adipose tissue inflammation in obesity
OBJECTIVE: Obesity is associated with insulin resistance and adipose tissue inflammation. Reactive oxygen species (ROS) increase in adipose tissue during the development of obesity. We previously showed that in response to excess nutrients like glucose and palmitate, adipocytes generated ROS via NAD...
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Udgivet i: | Arterioscler Thromb Vasc Biol |
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Main Authors: | , , , , , , |
Format: | Artigo |
Sprog: | Inglês |
Udgivet: |
2016
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Fag: | |
Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5323321/ https://ncbi.nlm.nih.gov/pubmed/28062496 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.116.308749 |
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