Adipocyte-specific deficiency of NADPH oxidase 4 delays the onset of insulin resistance and attenuates adipose tissue inflammation in obesity

OBJECTIVE: Obesity is associated with insulin resistance and adipose tissue inflammation. Reactive oxygen species (ROS) increase in adipose tissue during the development of obesity. We previously showed that in response to excess nutrients like glucose and palmitate, adipocytes generated ROS via NAD...

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Publicat a:Arterioscler Thromb Vasc Biol
Autors principals: Den Hartigh, Laura J., Omer, Mohamed, Goodspeed, Leela, Wang, Shari, Wietecha, Tomasz, O’Brien, Kevin D., Han, Chang Yeop
Format: Artigo
Idioma:Inglês
Publicat: 2016
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5323321/
https://ncbi.nlm.nih.gov/pubmed/28062496
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.116.308749
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