Superior anti-tumor efficacy of diisopropylamine dichloroacetate compared with dichloroacetate in a subcutaneous transplantation breast tumor model

Dichloroacetate (DCA), an inhibitor of pyruvate dehydrogenase kinase, has anti-tumor properties in various carcinoma models. Diisopropylamine dichloroacetate (DADA), an over-the-counter drug for chronic liver disease, is a derivative of DCA. To date, few studies have evaluated the anticancer potenti...

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Vydáno v:Oncotarget
Hlavní autoři: Su, Lei, Zhang, Hailin, Yan, Chen, Chen, Aiping, Meng, Gang, Wei, Jiwu, Yu, Decai, Ding, Yitao
Médium: Artigo
Jazyk:Inglês
Vydáno: Impact Journals LLC 2016
Témata:
Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5323187/
https://ncbi.nlm.nih.gov/pubmed/27582548
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.11609
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