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Characterizing and targeting PDGFRA alterations in pediatric high-grade glioma
Pediatric high-grade glioma (HGG, WHO Grade III and IV) is a devastating brain tumor with a median survival of less than two years. PDGFRA is frequently mutated/amplified in pediatric HGG, but the significance of this finding has not been fully characterized. We hypothesize that alterations of PDGFR...
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| Publicado en: | Oncotarget |
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| Autores principales: | , , , , , , , , , , , , , , , , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Impact Journals LLC
2016
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5323185/ https://ncbi.nlm.nih.gov/pubmed/27582545 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.11602 |
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