A quantitative model for the rate-limiting process of UGA alternative assignments to stop and selenocysteine codons

Ambiguity in genetic codes exists in cases where certain stop codons are alternatively used to encode non-canonical amino acids. In selenoprotein transcripts, the UGA codon may either represent a translation termination signal or a selenocysteine (Sec) codon. Translating UGA to Sec requires selenium...

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Veröffentlicht in:PLoS Comput Biol
Hauptverfasser: Chen, Yen-Fu, Lin, Hsiu-Chuan, Chuang, Kai-Neng, Lin, Chih-Hsu, Yen, Hsueh-Chi S., Yeang, Chen-Hsiang
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2017
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Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5323020/
https://ncbi.nlm.nih.gov/pubmed/28178267
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1005367
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