Galectin-3, histone deacetylases, and Hedgehog signaling: Possible convergent targets in schistosomiasis-induced liver fibrosis

Schistosomiasis affects approximately 240 million people in the world. Schistosoma mansoni eggs in the liver induce periportal fibrosis and hepatic failure driven by monocyte recruitment and macrophage activation, resulting in robust Th2 response. Here, we suggested a possible involvement of Galecti...

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Dettagli Bibliografici
Pubblicato in:PLoS Negl Trop Dis
Autori principali: de Oliveira, Felipe Leite, Carneiro, Katia, Brito, José Marques, Cabanel, Mariana, Pereira, Jonathas Xavier, Paiva, Ligia de Almeida, Syn, Wingkin, Henderson, Neil C., El-Cheikh, Marcia Cury
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2017
Soggetti:
Review
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5322873/
https://ncbi.nlm.nih.gov/pubmed/28231240
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0005137
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