Galectin-3, histone deacetylases, and Hedgehog signaling: Possible convergent targets in schistosomiasis-induced liver fibrosis

Schistosomiasis affects approximately 240 million people in the world. Schistosoma mansoni eggs in the liver induce periportal fibrosis and hepatic failure driven by monocyte recruitment and macrophage activation, resulting in robust Th2 response. Here, we suggested a possible involvement of Galecti...

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Detalhes bibliográficos
Publicado no:PLoS Negl Trop Dis
Main Authors: de Oliveira, Felipe Leite, Carneiro, Katia, Brito, José Marques, Cabanel, Mariana, Pereira, Jonathas Xavier, Paiva, Ligia de Almeida, Syn, Wingkin, Henderson, Neil C., El-Cheikh, Marcia Cury
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Review
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5322873/
https://ncbi.nlm.nih.gov/pubmed/28231240
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0005137
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