Playing hide and seek with repeats in local and global de novo transcriptome assembly of short RNA-seq reads

BACKGROUND: The main challenge in de novo genome assembly of DNA-seq data is certainly to deal with repeats that are longer than the reads. In de novo transcriptome assembly of RNA-seq reads, on the other hand, this problem has been underestimated so far. Even though we have fewer and shorter repeat...

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Salvato in:
Dettagli Bibliografici
Pubblicato in:Algorithms Mol Biol
Autori principali: Lima, Leandro, Sinaimeri, Blerina, Sacomoto, Gustavo, Lopez-Maestre, Helene, Marchet, Camille, Miele, Vincent, Sagot, Marie-France, Lacroix, Vincent
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2017
Soggetti:
Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5322684/
https://ncbi.nlm.nih.gov/pubmed/28250805
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13015-017-0091-2
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