Playing hide and seek with repeats in local and global de novo transcriptome assembly of short RNA-seq reads

BACKGROUND: The main challenge in de novo genome assembly of DNA-seq data is certainly to deal with repeats that are longer than the reads. In de novo transcriptome assembly of RNA-seq reads, on the other hand, this problem has been underestimated so far. Even though we have fewer and shorter repeat...

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Detalhes bibliográficos
Publicado no:Algorithms Mol Biol
Main Authors: Lima, Leandro, Sinaimeri, Blerina, Sacomoto, Gustavo, Lopez-Maestre, Helene, Marchet, Camille, Miele, Vincent, Sagot, Marie-France, Lacroix, Vincent
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2017
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5322684/
https://ncbi.nlm.nih.gov/pubmed/28250805
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13015-017-0091-2
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