Catching moving targets: cancer stem cell hierarchies, therapy-resistance & considerations for clinical intervention

It is widely believed that targeting the tumour-initiating cancer stem cell (CSC) component of malignancy has great therapeutic potential, particularly in therapy-resistant disease. However, despite concerted efforts, CSC-targeting strategies have not been efficiently translated to the clinic. This...

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Bibliografiske detaljer
Udgivet i:Mol Cancer
Main Authors: Gasch, Claudia, Ffrench, Brendan, O’Leary, John J., Gallagher, Michael F.
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2017
Fag:
Review
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5322629/
https://ncbi.nlm.nih.gov/pubmed/28228161
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12943-017-0601-3
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