SF3B1 mutations are associated with alternative splicing in uveal melanoma

Uveal melanoma, the most common eye malignancy causes severe visual morbidity and is fatal in about 50% of patients. Primary uveal melanoma can be cured by surgery or radiotherapy, but the metastatic disease is treatment refractory. To understand comprehensively uveal melanoma genetics, we performed...

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Pubblicato in:Cancer Discov
Autori principali: Furney, Simon J., Pedersen, Malin, Gentien, David, Dumont, Amaury G., Rapinat, Audrey, Desjardins, Laurence, Turajlic, Samra, Piperno-Neumann, Sophie, de la Grange, Pierre, Roman-Roman, Sergio, Stern, Marc-Henri, Marais, Richard
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2013
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5321577/
https://ncbi.nlm.nih.gov/pubmed/23861464
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2159-8290.CD-13-0330
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