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Establishment of novel cell lines recapitulating the genetic landscape of uveal melanoma and preclinical validation of mTOR as a therapeutic target

Uveal melanoma (UM) is the most common primary tumor of the eye in adults. There is no standard adjuvant treatment to prevent metastasis and no effective therapy in the metastatic setting. We have established a unique panel of 7 UM cell lines from either patient's tumors or patient‐derived tumo...

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Detalhes bibliográficos
Publicado no:Mol Oncol
Main Authors: Amirouchene-Angelozzi, Nabil, Nemati, Fariba, Gentien, David, Nicolas, André, Dumont, Amaury, Carita, Guillaume, Camonis, Jacques, Desjardins, Laurence, Cassoux, Nathalie, Piperno-Neumann, Sophie, Mariani, Pascale, Sastre, Xavier, Decaudin, Didier, Roman-Roman, Sergio
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5528590/
https://ncbi.nlm.nih.gov/pubmed/24994677
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molonc.2014.06.004
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