Establishment of novel cell lines recapitulating the genetic landscape of uveal melanoma and preclinical validation of mTOR as a therapeutic target

Uveal melanoma (UM) is the most common primary tumor of the eye in adults. There is no standard adjuvant treatment to prevent metastasis and no effective therapy in the metastatic setting. We have established a unique panel of 7 UM cell lines from either patient's tumors or patient‐derived tumo...

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Enregistré dans:
Détails bibliographiques
Publié dans:Mol Oncol
Auteurs principaux: Amirouchene-Angelozzi, Nabil, Nemati, Fariba, Gentien, David, Nicolas, André, Dumont, Amaury, Carita, Guillaume, Camonis, Jacques, Desjardins, Laurence, Cassoux, Nathalie, Piperno-Neumann, Sophie, Mariani, Pascale, Sastre, Xavier, Decaudin, Didier, Roman-Roman, Sergio
Format: Artigo
Langue:Inglês
Publié: John Wiley and Sons Inc. 2014
Sujets:
Research Articles
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5528590/
https://ncbi.nlm.nih.gov/pubmed/24994677
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molonc.2014.06.004
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