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Targeting Non-Catalytic Cysteine Residues Through Structure-Guided Drug Discovery

The targeting of non-catalytic cysteine residues with small molecules is drawing increased attention from drug discovery scientists and chemical biologists. From a biological perspective, genomic and proteomic studies have revealed the presence of cysteine mutations in several oncogenic proteins, su...

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Detalhes bibliográficos
Publicado no:Curr Top Med Chem
Main Authors: Hallenbeck, Kenneth K., Turner, David M., Renslo, Adam R., Arkin, Michelle R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5321175/
https://ncbi.nlm.nih.gov/pubmed/27449257
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