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DYRK1A regulates Hap1–Dcaf7/WDR68 binding with implication for delayed growth in Down syndrome
Huntingtin-associated protein 1 (Hap1) is known to be critical for postnatal hypothalamic function and growth. Hap1 forms stigmoid bodies (SBs), unique neuronal cytoplasmic inclusions of unknown function that are enriched in hypothalamic neurons. Here we developed a simple strategy to isolate the SB...
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| Izdano u: | Proc Natl Acad Sci U S A |
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| Glavni autori: | , , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
National Academy of Sciences
2017
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5321030/ https://ncbi.nlm.nih.gov/pubmed/28137862 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1614893114 |
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