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HIV-1 Vpr hijacks EDD-DYRK2-DDB1(DCAF1) to disrupt centrosome homeostasis
Viruses exploit the host cell machinery for their own profit. To evade innate immune sensing and promote viral replication, HIV type 1 (HIV-1) subverts DNA repair regulatory proteins and induces G(2)/M arrest. The preintegration complex of HIV-1 is known to traffic along microtubules and accumulate...
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| Publicado no: | J Biol Chem |
|---|---|
| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6005440/ https://ncbi.nlm.nih.gov/pubmed/29724823 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA117.001444 |
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