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O-GlcNAc transferase regulates excitatory synapse maturity

Experience-driven synaptic plasticity is believed to underlie adaptive behavior by rearranging the way neuronal circuits process information. We have previously discovered that O-GlcNAc transferase (OGT), an enzyme that modifies protein function by attaching β–N-acetylglucosamine (GlcNAc) to serine...

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Détails bibliographiques
Publié dans:Proc Natl Acad Sci U S A
Auteurs principaux: Lagerlöf, Olof, Hart, Gerald W., Huganir, Richard L.
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 2017
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5320993/
https://ncbi.nlm.nih.gov/pubmed/28143929
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1621367114
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