Genomic Instability Is Induced by Persistent Proliferation of Cells Undergoing Epithelial-to-Mesenchymal Transition

TGFβ secreted by tumor stroma induces Epithelial-to-Mesenchymal Transition (EMT) in cancer cells, a reversible phenotype linked to cancer progression and drug resistance. However, exposure to stromal signals may also lead to heritable changes in cancer cells, which are poorly understood. We show tha...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Cell Rep
Main Authors: Comaills, Valentine, Kabeche, Lilian, Morris, Robert, Buisson, Rémi, Yu, Min, Madden, Marissa Wells, LiCausi, Joseph A., Boukhali, Myriam, Tajima, Ken, Pan, Shiwei, Aceto, Nicola, Sil, Srinjoy, Zheng, Yu, Sundaresan, Tilak, Yae, Toshifumi, Jordan, Nicole Vincent, Miyamoto, David T., Ting, David T., Ramaswamy, Sridhar, Haas, Wilhelm, Zou, Lee, Haber, Daniel A., Maheswaran, Shyamala
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5320932/
https://ncbi.nlm.nih.gov/pubmed/27926867
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2016.11.022
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados